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Hydrophilic Matrix Tablets Oral Controlled Release Hardcover Samuel R Pygall 2014

Hydrophilic Matrix Tablets Oral Controlled Release Hardcover Samuel R Pygall 2014

$ 94.49

Hydrophilic Matrix Tablets for Oral Controlled Release, Hardcover by Timmins, Peter (EDT); Pygall, Samuel R. (EDT); Melia, Colin D. (EDT), ISBN 1493915185, ISBN-13 9781493915187, Brand New, Free shipp...

Description

Hydrophilic Matrix Tablets for Oral Controlled Release, Hardcover by Timmins, Peter (EDT); Pygall, Samuel R. (EDT); Melia, Colin D. (EDT), ISBN 1493915185, ISBN-13 9781493915187, Brand New, Free shipping in the US This detailed volume addresses key issues and subtle nuances involved in developing hydrophilic matrix tablets as an approach to oral controlled release. It brings together information from more than five decades of research and development on hydrophilic matrix tablets and provides perspective on contemporary issues. Twelve comprehensive chapters explore a variety of topics including polymers (hypromellose, natural polysaccharides and polyethylene oxide) and their utilization in hydrophilic matrices, critical interactions impacting tablet performance, in vitro physical and imaging techniques, and microenvironmental pH control and mixed polymer approaches, among others. In one collective volume, Hydrophilic Matrix Tablets for Oral Controlled Release provides a single source of current knowledge, including sections of previously unpublished data. It is an important resource for industrial and academic scientists investigating and developing these oral controlled release formulations.

Specifics

Author

Samuel R. Pygall

Dewey Decimal

615.19

Dewey Edition

23

Format

Hardcover

ISBN-10

1493915185

ISBN-13

9781493915187

Illustrated

Yes

Intended Audience

Scholarly & Professional

Item Length

9.3 in

Item Weight

242.6 Oz

Item Width

6.1 in

LC Classification Number

RS400-431

LCCN

2014-949342

Language

English

Number of Pages

IX, 326 Pages

Number of Volumes

1 vol.

Publication Name

Hydrophilic Matrix Tablets for Oral Controlled Release

Publication Year

2014

Publisher

Springer New York

Series

Aaps Advances in the Pharmaceutical Sciences Ser.

Series Volume Number

16

Subject

Pharmacy, Pharmacology, Chemistry / Organic

Subject Area

Science, Medical

Synopsis

This detailed volume addresses key issues and subtle nuances involved in developing hydrophilic matrix tablets as an approach to oral controlled release. It brings together information from more than five decades of research and development on hydrophilic matrix tablets and provides perspective on contemporary issues. Twelve comprehensive chapters explore a variety of topics including polymers (hypromellose, natural polysaccharides and polyethylene oxide) and their utilization in hydrophilic matrices, critical interactions impacting tablet performance, in vitro physical and imaging techniques, and microenvironmental pH control and mixed polymer approaches, among others. In one collective volume, Hydrophilic Matrix Tablets for Oral Controlled Release provides a single source of current knowledge, including sections of previously unpublished data. It is an important resource for industrial and academic scientists investigating and developing these oral controlled release formulations.

Table Of Content

1 Hydrophilic Matrix Dosage Forms: Definitions, General Attributes and the Evolution of Clinical Utilization.- 2 Design and Evaluation of Hydroxypropyl Methylcellulose Matrix Tablets for Oral Controlled Release: a Historical Perspective.- 3 An Industrial Perspective on Hydrophilic Matrix Tablets based on Hyproxypropyl Methylcellulose (Hypromellose).- 4 Natural Polysaccharides in Hydrophilic Matrices.- 5 Applications of Polyethylene Oxide (POLYOX) in Hydrophilic Matrices.- 6 A Formulation Development Perspective on Critical Interactions Affecting the Performance of Hydrophilic Matrix Tablets.- 7 In vitro Physical and Imaging Techniques to Evaluate Drug Release Mechanisms from Hydrophilic Matrix Tablets.- 8 Physiologically-Based Pharmacokinetic Modelling in the Development and Evaluation of Hydrophilic Matrix Tablets.- 9 Approaches to Rapid In Vivo Optimization of Hydrophilic Matrix Tablets.- 10 Extrusion: an Enabling Technology for Controlled Release Hydrophilic Matrix Systems.- 11 Microenvironmental pH Control and Mixed Polymer Approaches to Optimize Drug Delivery with Hydrophilic Matrix Tablets.- 12 Evolving Biopharmaceutics Perspectives for Hydrophilic Matrix Tablets: Dosage Form-Food Interactions and Dosage Form Gastrointestinal Tract Interactions.

Type

Textbook

brand

Springer New York

gtin13

9781493915187

Reviews

  1. finrod024bb6

    This book is a must-have for anyone working in pharmaceutical sciences! It offers in-depth insights into hydrophilic matrix tablets, covering decades of research in a clear, well-organized way. The expertise of the editors shines through, making complex topics easy to understand. Perfect for researchers and professionals looking to master controlled-release formulations. Highly recommended!